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Electron ionization mass spectra of some substituted stereoisomeric 1,6,7,11b‐tetrahydro‐ 2h,4H [1,3]oxazino[4,3‐a]‐isoquinolines and 1,6,7,11b‐tetrahydro‐ 2H [1,3]oxazino [4,3‐a]‐isoquinolin‐4‐ones 1
Author(s) -
Joutsiniemi Karoliina,
Vainiotalo Pirjo,
Lázár László,
Fülöp Ferenc,
Bernáth Gábor
Publication year - 1995
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290091105
Subject(s) - chemistry , fragmentation (computing) , electron ionization , mass spectrum , oxazole , ionization , dissociation (chemistry) , collision induced dissociation , ion , mass spectrometry , spectral line , metastability , analytical chemistry (journal) , stereochemistry , organic chemistry , tandem mass spectrometry , chromatography , physics , astronomy , computer science , operating system
The mass spectra often substituted oxazino[4,3‐a]isoquinolines, two isoquino[2,1‐c][1,3]benzoxazines and seven substituted oxazino[4,3‐a]isoquinolin‐4‐ones were recorded under electron impact ionization. Fragmentations were examined by metastable ion analysis, collision induced dissociation and exact mass measurement. The oxazinoisoquinolines and oxazinoisoquinolin‐4‐ones behaved similarly, although there were a few differences in the fragmentation and especially in the peak intensities. The most important fragmentation began with the opening of the oxazole ring. The substituents affected the fragmentation of the isomeric compounds, whereas the spectra of the stereoisomeric compounds were identical. The two isoquinobenzoxazines differed noticeably from the other compounds in their fragmentation behaviour; the additional phenyl ring prompted entirely new fragmentations unique to this structure.