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Mass spectrometry of cyanocobalamine, glucose and raffinose in the solid state and on a disperse oxide surface
Author(s) -
Pokrovskiy V. A.,
Galagan N. P.,
Dembnovetskaya L. I.
Publication year - 1995
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290090710
Subject(s) - chemistry , raffinose , adsorption , mass spectrometry , oxide , fast atom bombardment , inorganic chemistry , chromatography , organic chemistry , sucrose
The biologically active systems were synthesized by adsorption of vitamin B 12 , glucose and raffinose on an ultrafine oxide surface and studied by means of thermal analysis and temperature‐programmed mass spectrometry. It is shown that adsorption of cyanocobalamine (B 12 ) on the silica surface transformed the propionamide group to a weakly bound form. The role of the charged cobalt atom and of the propionamide and benzimide groups in the adsorption mechanism is discussed. Experimental data were obtained confirming the stable adsorption of glucose and raffinose on an ultrafine pyrogenic silica surface modified by amino groups.