Premium
Detection of hydrogen‐bonded supramolecular complexes using electrospray ionization from chloroform
Author(s) -
Cheng Xueheng,
Gao Quanyin,
Smith Richard D.,
Simanek Eric E.,
Mammen Mathai,
Whitesides George M.
Publication year - 1995
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290090410
Subject(s) - chemistry , supramolecular chemistry , electrospray ionization , chloroform , dissociation (chemistry) , stoichiometry , electrospray , non covalent interactions , ionization , ion , hydrogen bond , photochemistry , analytical chemistry (journal) , molecule , chromatography , organic chemistry
The stoichiometry of a noncovalent, hydrogen‐bonded supramolecular complex, hub(M) 3 ·RCA 3 , was characterized using electrospray ionization from chloroform. The intact (1:3) complex was observed in the negative‐ion mode as a Cl − ‐bound species using Ph 4 PCl as the source of the charge donor. Collisionally and thermally induced dissociation of the (1:3) complex resulted in the simultaneous loss of all the three RCA units, indicating a cooperative binding of RCA units in the (1:3) complex. These results suggest that the attachment of small, organic‐soluble ions may be a useful technique for mass spectrometric characterization of neutral supramolecular complexes that are stable or soluble only in non‐polar organic solvents.