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A potential problem in the analysis of toxaphene by electron‐capture negative‐ion mass spectrometry
Author(s) -
Lau Benjamin P.Y.,
Weber Dorcas,
Andrews Paul
Publication year - 1994
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290081011
Subject(s) - congener , chemistry , toxaphene , electron ionization , mass spectrometry , electron capture , mass spectrum , chemical ionization , gas chromatography , ion , chromatography , polyatomic ion , environmental chemistry , analytical chemistry (journal) , ionization , organic chemistry , pesticide , ecology , biology
On analyzing 11 pure individual toxaphene congeners, it was noted that a nonachloro congener (2,2,5,5,8,8,9,10,10‐nonachlorobornane, Parlar's No. 62) failed to produce a reasonable [M–Cl] − response under our electron‐capture negative‐ion (ECNI) chemical ionization conditions. On the other hand, this congener gave a stronger response than other nonachlorobornane congeners in electron impact (EI) mode. Based on EI mass spectra data as well as electron capture gas chromatographic results, this congener is one of the major components in commercial toxaphene and is also present in fish and cod liver oil samples. This congener‐specific discriminatory effect raises concern about possible false negative results from the ECNI/selective‐ion monitoring analyses.