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Matrix‐assisted laser desorption/ionization of restriction enzyme‐digested DNA
Author(s) -
Tang K.,
Allman S. L.,
Chen C. H.,
Cháng L. Y.,
Schell M.
Publication year - 1994
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290080212
Subject(s) - chemistry , restriction enzyme , mass spectrometry , matrix assisted laser desorption electrospray ionization , oligonucleotide , ionization , desorption , dna , soft laser desorption , matrix (chemical analysis) , matrix assisted laser desorption/ionization , surface enhanced laser desorption/ionization , laser , chromatography , enzyme , atmospheric pressure laser ionization , analytical chemistry (journal) , sample preparation in mass spectrometry , electron ionization , biochemistry , electrospray ionization , ion , optics , organic chemistry , physics , adsorption
Matrix‐assisted laser desorption/ionization, by a time‐of‐flight mass spectrometer, has been successfully used for detection of restriction enzyme‐digested DNA. However, the oligonucleotide segments detected correspond to the molecular weights of single strands.