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Mass spectrometric studies on azasqualenes, a class of 2,3‐oxidosqualene cyclase inhibitors
Author(s) -
Ceruti Maurizio,
Seraglia Roberta,
Traldi Pictro
Publication year - 1994
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290080112
Subject(s) - chemistry , fragmentation (computing) , electron ionization , mass spectrometry , ionization , ion , analytical chemistry (journal) , chromatography , organic chemistry , computer science , operating system
The mass spectrometric behaviour of a series of azasqualenes and azasqualanes has been studied by two different instruments, a double focusing machine and an ion‐trap mass spectrometer (ITMS). The high abundances of fragmentation products obtained using the former indicate that with ITMS, processes additional to electron ionization must be present, leading to molecular species with lower internal energy contents.