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Verification of the position of the phosphate group in some synthetic phosphopeptides by fast‐atom bombardment and tandem mass spectrometry
Author(s) -
Nijenhuis A. A.,
Fokkens R. H.,
Nibbering N. M. M.,
van Oijen A. H.,
de Bont H. B. A.,
Liskamp R. M. J.,
van Boom J. H.
Publication year - 1993
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290070818
Subject(s) - chemistry , fast atom bombardment , phosphoric acid , phosphate , tandem mass spectrometry , tandem , mass spectrometry , ion , group (periodic table) , analytical chemistry (journal) , chromatography , organic chemistry , materials science , composite material
Some synthetically obtained linear and cyclic phosphopeptides of low molecular weight have been studied by fast‐atom bombardment and tandem mass spectrometry to verify the position of the phosphate group in these compounds. Based upon the occurrence/non‐occurrence of loss of phosphoric acid from low abundance fragment ions induced by low‐ and high‐energy collisions with target gases, it is shown that the position of the phosphate group in the phosphopeptides studied can be determined unequivocally.