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Investigation of some thiosulfonate derivatives by means of chemical ionization and tandem mass spectrometry
Author(s) -
Curcuruto O.,
Winders J.,
Franchi D.,
Hamdan M.
Publication year - 1993
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290070724
Subject(s) - chemistry , electron ionization , chemical ionization , mass spectrum , mass spectrometry , collision induced dissociation , ionization , ion , tandem mass spectrometry , proton affinity , molecule , dissociation (chemistry) , ion source , analytical chemistry (journal) , chromatography , organic chemistry , protonation
A number of thiosulfonate derivatives have been investigated by means of ammonia chemical ionization (NH 3 ‐CI), electron impact ionization (El) and mass‐selected collision induced dissociation (CID). For most of the compounds investigated, the NH 3 ‐CI positive‐ion mass spectra exhibit the addition ion, [M + NH 4 ] + , as the dominant species, which implies that the proton affinities of the compounds investigated are less than the proton affinity of NH 3 . Deviation from true chemical ionization conditions resulted in efficient dissociation of the addition ion to yield substantial amounts of the protomated molecule, [M + H] + . The major fragment ions observed in the EI mass spectra and in the CID spectra indicate the cleavage of the sulfur‐sulfur bond to be more efficient than other competing cleavages. This and other experimental observations are discussed.