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Electron impact mass spectrometry and metastable ion studies on 2‐[3‐hydroxy‐2‐pyridyi]‐2‐(3h)‐thiazolimine and 1,3,4‐thiadiazine derivatives
Author(s) -
Hadjieva P.,
Kalcheva V.,
Tosheva M.,
Danieli B.,
Catinella S.
Publication year - 1993
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290070609
Subject(s) - chemistry , fragmentation (computing) , thiazoline , metastability , ion , mass spectrometry , electron ionization , deuterium , bond cleavage , ring (chemistry) , amine gas treating , computational chemistry , analytical chemistry (journal) , medicinal chemistry , organic chemistry , chromatography , atomic physics , ionization , physics , computer science , catalysis , operating system
The mass spectrometric behaviour of some 2‐[3‐hydroxy‐pyridyl]‐2‐(3H)‐thiazolimine and 1,3,4‐thiadiazine derivatives was studied in detail under electron ionizing conditions by means of accurate mass measurements, deuterium‐labelling experiments and metastable ion studies. The resultant fragmentation patterns were highly complicated with cleavage of the amine bond and of the thiazoline ring. The main differences between the decomposition mechanism of thiazoline and thiadiazine derivatives lies in the retro‐synthetic ring transformation processes, observed in the case of thiadiazine compounds only.