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Thin layer chromatography/mass spectrometry: The advantages of tandem mass spectrometry
Author(s) -
Monaghan J. J.,
Morden W. E.,
Johnson T.,
Wilson I. D.,
Martin P.
Publication year - 1992
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290061005
Subject(s) - chemistry , mass spectrometry , chromatography , tandem mass spectrometry , thin layer chromatography , analyte , sample preparation in mass spectrometry , protein mass spectrometry , analytical chemistry (journal) , tandem , electrospray ionization , materials science , composite material
The results of thin layer chromatography/mass spectrometry (TLC/MS) and thin layer chromatography/tandem mass spectrometry (TLC/MS/MS) experiments are described. Spectra from the analytes were obtained directly from the absorbent without the need for extraction prior to analysis by mass spectrometry. These results illustrate the added specificity that the tandem mass spectrometer can afford in the detection and characterization of a range of compounds separated by TLC.