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Synchronized collision‐cell energy ramping. Improving the quality of product‐ion spectra
Author(s) -
Fitton E. M.,
Monaghan J. J.,
Morden W. E.
Publication year - 1992
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290060409
Subject(s) - collision , chemistry , analyser , ion , collision induced dissociation , spectrum analyzer , mass spectrometry , spectral line , atomic physics , voltage , quadrupole , quadrupole ion trap , dissociation (chemistry) , generator (circuit theory) , physics , ion trap , optics , tandem mass spectrometry , power (physics) , computer security , organic chemistry , chromatography , quantum mechanics , astronomy , computer science
The design and use of an RF‐only collision‐cell ramp generator is described. The generatio controls the collision energy voltage applied to the RF‐only collision cell in a hybrid mass spectrometer of BEqQ geometry. The generator enables the collision‐cell voltage to be increased or decreased in a linear ramp, over the full 500 V available. The start/stop functions of the ramp are synchronized under data system control to the scan of the quadrupole mass analyser. The collision‐induced dissociation spectra so produced show an increase in the product ion abundance.