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The intramolecular migration of a trimethylsilyl group located α to a sulfone in substituted cyclohexyl systems
Author(s) -
Wood K. V.,
Rothwell A. P.,
Anderson M. B.,
Fuchs P. L.
Publication year - 1990
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290040102
Subject(s) - chemistry , intramolecular force , sulfone , moiety , trimethylsilyl , protonation , ring (chemistry) , group (periodic table) , medicinal chemistry , stereochemistry , ion , organic chemistry
The intramolecular migration of a trimethylsilyl moiety α to a sulfone group of some modified cylcohexyl ring systems is investigated. The large difference in the relative abundance of this rearrangement ion for similar compounds is related to the stability of the protonated species.