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Instrument‐independent database for collisionally activated dissociation in radiofrequency‐only quadrupoles. Single‐collision versus multiple‐collision conditions
Author(s) -
Martinez Richard I.,
Ganguli B.,
Cooks R. G.
Publication year - 1989
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290031206
Subject(s) - chemistry , collision , dissociation (chemistry) , ion , branching (polymer chemistry) , collision induced dissociation , analytical chemistry (journal) , mass spectrometry , chromatography , tandem mass spectrometry , organic chemistry , computer science , computer security
The collisionally actived dissociation (CAD) of the acetone cation ( m / z 58) and of the acetyl cation ( m / z 43) from acetone were studied under single‐collision and multiple‐collision conditions. A kinetics‐based measurement protocol developed at the National Institute of Standards and Technology was used to measure the CAD spectra (i.e., the product distributions (branching ratios) of the CAD fragment ions). A protocol is proposed for a second interlaboratory round robin to explore the feasibility (or lack thereof) of measuring standardized, instrument‐independent CAD spectra under multiple‐collision conditions.