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Characterization of high molecular weight macrocycles by desorption chemical ionization mass spectrometry
Author(s) -
Guglielmetti Gianfranco,
Dalcanale Enrico,
Bonsignore Stefanio,
Vincenti Marco,
Busch K. L.
Publication year - 1989
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290030405
Subject(s) - chemistry , fragmentation (computing) , mass spectrum , mass spectrometry , ionization , desorption , chemical ionization , analytical chemistry (journal) , ion , polyatomic ion , ambient ionization , chromatography , organic chemistry , adsorption , computer science , operating system
A series of multi‐armed macrocycles with molecular weights up to 4400 Da was studied by desorption chemical ionization. Both negative‐ and positive‐ion spectra exhibited excellent signal‐to‐noise ratio, despite the limited amount of material sampled (0.1–1 pmol). The molecular ions generally represent the base peaks of the spectra, but the extent of fragmentation increases as the source temperature is raised.