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Application of continuous‐flow liquid chromatography/fast‐atom bombardment mass spectrometry to the analysis of diagnostic acylcarnitines in human urine
Author(s) -
Norwood Daniel L.,
Kodo Naoki,
Millington David S.,
Gaskell S. J.
Publication year - 1988
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290021205
Subject(s) - chemistry , fast atom bombardment , chromatography , mass spectrometry , urine , liquid chromatography–mass spectrometry , analytical chemistry (journal) , continuous flow , biochemistry , physics , mechanics
Acylcarnitine profiles of diagnostic value were generated from the equivalent of 0.1 μL of raw urine using the continuous‐flow liquid chromatography/fast‐atom bombardment mass spectrometry (LC/FAB‐MS) interface for sample introduction. Further analysis was accomplished by gradient LC/MS using a commercially available packed fused‐silica microbore column.