Application of continuous‐flow liquid chromatography/fast‐atom bombardment mass spectrometry to the analysis of diagnostic acylcarnitines in human urine | Zendy

Norwood Daniel L. | Zendy; Kodo Naoki | Zendy; Millington David S. | Zendy; Gaskell S. J. | Zendy

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Application of continuous‐flow liquid chromatography/fast‐atom bombardment mass spectrometry to the analysis of diagnostic acylcarnitines in human urine

Author(s) -

Norwood Daniel L.,

Kodo Naoki,

Millington David S.,

Gaskell S. J.

Publication year - 1988

Publication title -

rapid communications in mass spectrometry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.528

H-Index - 136

eISSN - 1097-0231

pISSN - 0951-4198

DOI - 10.1002/rcm.1290021205

Subject(s) - chemistry , fast atom bombardment , chromatography , mass spectrometry , urine , liquid chromatography–mass spectrometry , analytical chemistry (journal) , continuous flow , biochemistry , physics , mechanics

Acylcarnitine profiles of diagnostic value were generated from the equivalent of 0.1 μL of raw urine using the continuous‐flow liquid chromatography/fast‐atom bombardment mass spectrometry (LC/FAB‐MS) interface for sample introduction. Further analysis was accomplished by gradient LC/MS using a commercially available packed fused‐silica microbore column.

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