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An experimental investigation of the possibility of developing a database for tandem mass spectrometry using xqq instruments
Author(s) -
Dheandhanoo Seksan,
Boyd R. K.
Publication year - 1988
Publication title -
rapid communications in mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 136
eISSN - 1097-0231
pISSN - 0951-4198
DOI - 10.1002/rcm.1290021203
Subject(s) - chemistry , tandem , mass spectrometry , quadrupole , analytical chemistry (journal) , triple quadrupole mass spectrometer , dissociation (chemistry) , tandem mass spectrometry , collision induced dissociation , selected reaction monitoring , atomic physics , chromatography , aerospace engineering , physics , engineering
The NBS round‐robin protocol for testing the performance of XQQ tandem mass spectrometers (R.I. Martinez, Rapid Commun. Mass. Spectrom. 2, 8 (1988)) has been evaluated using a QQQ instrument which is significantly different in both the size of the quadrupole rods and the design from that used in the NBS work. The NBS experimental cross‐sections for the Ar +. /Ar charge‐transfer reactions were used to provide a calibration of target thickness in the present apparatus. The present experimental value of the reaction cross‐section for the N 2 +. /SF 6 system is 60 ± 3 Å 2 at the center‐of‐mass collision energy of 4.4 eV, in excellent agreement with the NBS literature value (55 Å 2 ). This result supports the view that a library of collisionally activated dissociation spectra is feasible provided that the instruments used are of dynamically correct design.