Premium
The mechanism of bacteriorhodopsin functioning. II. Ejection and injection of proton
Author(s) -
Krasnogolovets V. V.,
Protsenko N. A.,
Tomchuk P. M.
Publication year - 1988
Publication title -
international journal of quantum chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.484
H-Index - 105
eISSN - 1097-461X
pISSN - 0020-7608
DOI - 10.1002/qua.560330409
Subject(s) - bacteriorhodopsin , proton , chemistry , excitation , proton transport , halobacteriaceae , atomic physics , isomerization , channel (broadcasting) , retinal , chemical physics , molecular physics , physics , membrane , nuclear physics , biochemistry , quantum mechanics , halobacterium salinarum , electrical engineering , engineering , catalysis
Abstract Transmission of vibrational excitation energy conserved in cis ‐conformation of retinal to the outlet proton channel is considered from the perspective of quantum theory. A distribution of vibrational excitations in the channel is found; it allowed to calculate the magnitude of the directed drift proton current. The differences between velocities of proton movement in active and passive channels are considered. A transition of retinal from cis ‐ to all ‐ trans ‐ conformation with the subsequent capture of proton by Schiff base out of the inlet channel is described. The lack of proton in this channel, i.e., in the H‐bonded chain, is eliminated at the expense of the capture of a proton out of the cytoplasmic water enviroment. The correspondence between theoretically established states and spectroscopically identified forms of bacteriorhodopsin (inter‐mediates L, M, N, and O) is proposed.