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Effect of deuterium‐hydrogen exchange on the electrical conduction in lysozyme
Author(s) -
Behi Joy,
Bone Stephen,
Morgan Hywel,
Pethig Ronald
Publication year - 2009
Publication title -
international journal of quantum chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.484
H-Index - 105
eISSN - 1097-461X
pISSN - 0020-7608
DOI - 10.1002/qua.560220734
Subject(s) - deuterium , lysozyme , chemistry , thermal conduction , hydrogen , hydrogen–deuterium exchange , thermodynamics , atomic physics , physics , organic chemistry , biochemistry
The H 2 O and D 2 O sorption isotherms have been measured for lysozyme powders, as well as the extent of the deuterium‐hydrogen exchange as a function of D 2 O partial pressure. D 2 O appears to bind more strongly to lysozyme than H 2 O. There is a significant reduction in the steady‐state conductivity of lysozyme when sorbed water molecules are replaced by the same number of sorbed D 2 O molecules. This effect is taken as strong evidence that the dominant conduction process in lysozyme powder involves the transport of protons.