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Structure–Activity relationships in auxins
Author(s) -
Raghunathan S.,
Pattabhi Vasantha
Publication year - 1981
Publication title -
international journal of quantum chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.484
H-Index - 105
eISSN - 1097-461X
pISSN - 0020-7608
DOI - 10.1002/qua.560200114
Subject(s) - auxin , hormone , charge (physics) , chemistry , density functional theory , molecule , chemical physics , computational chemistry , stereochemistry , biophysics , biochemistry , physics , biology , organic chemistry , quantum mechanics , gene
Of the various theories proposed for auxin activity, the conformational change theory and the charge separation theory have received considerable attention. However, no conclusive theory collating molecular structure with hormonal activity has yet been established. We have studied the structural requirements for hormonal activity in plants through single crystal x‐ray studies, as well as through conformational and charge density calculations on a series of plant hormones. We find that the existing theories are inadequate in explaining the activity of several auxins. We propose that the size of the auxin molecule in conjunction with the charge separation serves as a possible mechanism of action in plant hormones.