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Possible viral involvement in human mammary carcinoma: A microwave and laser‐raman study
Author(s) -
Webb S. J.,
Lee R.,
Stoneham M. E.
Publication year - 2009
Publication title -
international journal of quantum chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.484
H-Index - 105
eISSN - 1097-461X
pISSN - 0020-7608
DOI - 10.1002/qua.560120728
Subject(s) - mammary carcinoma , raman spectroscopy , carcinoma , virus , cell culture , sarcoma , cancer research , biology , chemistry , pathology , medicine , virology , optics , physics , genetics
The microwave and laser‐Raman spectra of normal human mammary and mammary carcinoma cells indicate that resonances between 10 10 and 10 12 Hz exist in active cells. The spectra of both “normal” and carcinoma cells, from the same patients, displayed a splitting of the single spectra peaks seen in the spectra of normal cells. This same splitting of peaks was observed also when BHK cells, in tissue culture, were transformed into tumor cells by sarcoma viruses. The result suggests that in vivo coherent oscillations become resolved during the oncogenic process. In addition, females who later suffer mammary carcinoma may carry a latent oncogenic virus which becomes induced by pregnancy, menopause, and trauma. Thus mammary carcinoma, and indeed predisposition to the disease, may be diagnosed by the spectroscopic methods described.