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Some current models of carcinogenesis
Author(s) -
Löwdin PerOlov
Publication year - 2009
Publication title -
international journal of quantum chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.484
H-Index - 105
eISSN - 1097-461X
pISSN - 0020-7608
DOI - 10.1002/qua.560120720
Subject(s) - carcinogenesis , disturbance (geology) , connection (principal bundle) , current (fluid) , cancer , virus , biology , disease , genetic model , neuroscience , risk analysis (engineering) , computer science , genetics , computational biology , physics , medicine , mathematics , paleontology , geometry , gene , thermodynamics
The various models of carcinogenesis related to the genetic dogma are reviewed: the virus model, the somatic mutation model, and the reading‐error model. Also the electronic theory of cancer is discussed in this framework. It is emphasized that it is likely that cancer is a disease caused by a disturbance in the control of the cell differentiation, which may be different depending on whether the disturbance is caused by an external virus, radiation, or a chemical compound. Even some current models of aging are being briefly discussed in this connection.