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Evolution of conformational principles in nucleic acids
Author(s) -
Sundaralingam M.
Publication year - 2009
Publication title -
international journal of quantum chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.484
H-Index - 105
eISSN - 1097-461X
pISSN - 0020-7608
DOI - 10.1002/qua.560080713
Subject(s) - polynucleotide , nucleic acid , nucleic acid structure , nucleotide , chemistry , flexibility (engineering) , polypeptide chain , stereochemistry , amino acid , rna , biochemistry , mathematics , statistics , gene
The analysis of conformations of nucleic acids and polynucleotides have been greatly simplified by the important observations that the nucleotide building blocks exhibit two classes of preferred conformations and that the flexibility in the polynucleotide chain resides mainly in the internucleotide PO linkages.