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A 2D graphical representation of DNA sequence based on dual nucleotides and its application
Author(s) -
Liu Zanbo,
Liao Bo,
Zhu Wen,
Huang Guohua
Publication year - 2008
Publication title -
international journal of quantum chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.484
H-Index - 105
eISSN - 1097-461X
pISSN - 0020-7608
DOI - 10.1002/qua.21919
Subject(s) - nucleotide , dual (grammatical number) , sequence (biology) , dna , representation (politics) , computational biology , gene , biology , algorithm , genetics , computer science , art , literature , politics , political science , law
From the perspective of the neighboring dual nucleotides, we introduce a novel 2D graphical representation of DNA sequences based on the magic circle, which correspond to 16 dual nucleotides. So, we can reduce a DNA sequence into a plot set in two‐dimensional space and get a two‐component vector relatively to the introduced covariance matrix. The utility of our approach can be illustrated by the examination of similarities/dissimilarities among the complete coding sequences of β‐ globin gene belonging to 11 species. © 2008 Wiley Periodicals, Inc. Int J Quantum Chem, 2009