Ingenuity pathway analysis of the human cardiac cell Atlas identifies differences between right and left ventricular cardiomyocytes | Zendy

Prisco Sasha Z. | Zendy; Kazmirczak Felipe | Zendy; Thenappan Thenappan | Zendy; Prins Kurt W. | Zendy

Open Access

Ingenuity pathway analysis of the human cardiac cell Atlas identifies differences between right and left ventricular cardiomyocytes

Author(s) -

Prisco Sasha Z.,

Kazmirczak Felipe,

Thenappan Thenappan,

Prins Kurt W.

Publication year - 2022

Publication title -

pulmonary circulation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.791

H-Index - 40

ISSN - 2045-8940

DOI - 10.1002/pul2.12011

Subject(s) - ingenuity , medicine , left ventricles , cardiology , atlas (anatomy) , heart failure , cardiac ventricle , cardiac magnetic resonance , anatomy , radiology , magnetic resonance imaging , ventricle , neoclassical economics , economics

Pharmaceuticals for left ventricular (LV) dysfunction do not have similar success in right ventricular (RV) failure, which may reflect biological differences between the ventricles. In this study, we performed Ingenuity Pathway Analysis of the Human Cell Atlas to understand how the transcriptomic signatures of the RV and LV differ.

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