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Rhabdomyolysis associated with clozapine and haloperidol
Author(s) -
Lam Y. W. Francis
Publication year - 2020
Publication title -
the brown university psychopharmacology update
Language(s) - English
Resource type - Journals
eISSN - 1556-7532
pISSN - 1068-5308
DOI - 10.1002/pu.30652
Subject(s) - clozapine , haloperidol , rhabdomyolysis , medicine , schizophrenia (object oriented programming) , side effect (computer science) , antipsychotic , drug , antipsychotic drug , refractory (planetary science) , atypical antipsychotic , pharmacology , anesthesia , psychiatry , physics , astrobiology , computer science , programming language , dopamine
The atypical antipsychotic clozapine is primarily used for patients with treatment‐refractory schizophrenia. Despite the drug's efficacy, its usefulness is limited by the occurrence of significant side effects, such as life‐threatening agranulocytosis, which occurs in 1 to 2% of treated patients. Another rare yet dangerous side effect of clozapine is rhabdomyolysis.