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Evidence of benefit limited for treatments for Alzheimer's‐type dementia
Publication year - 2020
Publication title -
the brown university psychopharmacology update
Language(s) - English
Resource type - Journals
eISSN - 1556-7532
pISSN - 1068-5308
DOI - 10.1002/pu.30617
Subject(s) - dementia , medicine , placebo , alzheimer's disease , cholinesterase , meta analysis , cognition , psychiatry , disease , alternative medicine , pharmacology , pathology
A systematic review and meta‐analysis encompassing 66 studies has found limited evidence of benefits from medication treatments for clinical Alzheimer's‐type dementia. There was some evidence supporting cholinesterase inhibitors over placebo for cognitive and functional outcomes, but little evidence supporting any treatment for behavioral and psychological symptoms of dementia.