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Association of cardiovascular events with antidepressants in the elderly
Author(s) -
Lam Y. W. Francis
Publication year - 2020
Publication title -
the brown university psychopharmacology update
Language(s) - English
Resource type - Journals
eISSN - 1556-7532
pISSN - 1068-5308
DOI - 10.1002/pu.30580
Subject(s) - tricyclic , medicine , adverse effect , disease , reuptake inhibitor , depression (economics) , pharmacology , serotonin , receptor , economics , macroeconomics
Many patients with cardiovascular disease exhibit depressive symptoms and are treated with antidepressants. The literature has long suggested concerns regarding adverse effects of tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs) on the heart, including risk of arrhythmias. A recent study examined the relationship between antidepressants and adverse cardiovascular events in elderly patients with a history of cardiovascular disease.