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Single ketamine infusion with behavioral therapy improves outcomes in cocaine‐dependent patients
Publication year - 2019
Publication title -
the brown university psychopharmacology update
Language(s) - English
Resource type - Journals
eISSN - 1556-7532
pISSN - 1068-5308
DOI - 10.1002/pu.30484
Subject(s) - ketamine , midazolam , medicine , abstinence , craving , anesthesia , limiting , psychotherapist , addiction , psychology , clinical psychology , psychiatry , sedation , mechanical engineering , engineering
A five‐week trial involving 55 participants has concluded that a single infusion of ketamine in combination with a course of mindfulness‐based psychotherapy was more effective than midazolam with therapy in limiting craving and maintaining abstinence among individuals with cocaine dependence. The researchers found that participants receiving ketamine were 53% less likely to drop out of treatment or use cocaine in comparison with the midazolam group.