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Two antipsychotics fail to improve delirium over placebo in hospital patients
Publication year - 2019
Publication title -
the brown university psychopharmacology update
Language(s) - English
Resource type - Journals
eISSN - 1556-7532
pISSN - 1068-5308
DOI - 10.1002/pu.30393
Subject(s) - delirium , ziprasidone , medicine , haloperidol , placebo , intensive care unit , anesthesia , coma (optics) , intensive care medicine , schizophrenia (object oriented programming) , psychiatry , antipsychotic , alternative medicine , pathology , dopamine , physics , optics
Haloperidol and ziprasidone did not significantly alter the course of delirium compared with placebo in a group of patients with acute respiratory failure or shock in a hospital intensive care unit (ICU), a study has found. Researchers had hypothesized that both the typical and atypical antipsychotics would result in a shorter duration of delirium and coma than placebo.