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Prazosin study finds reduction in quantity, not frequency, of alcohol use
Publication year - 2018
Publication title -
the brown university psychopharmacology update
Language(s) - English
Resource type - Journals
eISSN - 1556-7532
pISSN - 1068-5308
DOI - 10.1002/pu.30374
Subject(s) - prazosin , placebo , alcohol , medicine , antagonist , reduction (mathematics) , adrenergic receptor , anesthesia , pharmacology , receptor , mathematics , chemistry , biochemistry , alternative medicine , geometry , pathology
A 12‐week double‐blind study involving individuals with alcohol use disorder has found that the alpha‐1 adrenergic receptor antagonist prazosin reduced the likelihood of heavy drinking relative to placebo. Prazosin did not reduce the frequency of drinking as measured by the number of drinking days per week.