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Antibiotic affecting risperidone and venlafaxine concentrations
Author(s) -
Lam Y. W. Francis
Publication year - 2017
Publication title -
the brown university psychopharmacology update
Language(s) - English
Resource type - Journals
eISSN - 1556-7532
pISSN - 1068-5308
DOI - 10.1002/pu.30250
Subject(s) - venlafaxine , risperidone , metronidazole , medicine , pharmacology , pharmacotherapy , escitalopram , antibiotics , drug , metabolite , active metabolite , regimen , psychiatry , pharmacokinetics , schizophrenia (object oriented programming) , antidepressant , microbiology and biotechnology , biology , anxiety
Psychiatric patients often have concurrent medical conditions that require management with pharmacotherapy, thereby increasing the potential for drug‐drug interactions. The following case involved an occurrence of increased risperidone and venlafaxine concentrations and a change in the metabolic ratios between the parent compound and the respective metabolite after the antibiotic metronidazole was added to an ongoing regimen of both psychotropics.