Premium
Valproate and paliperidone interaction
Author(s) -
Lam Y. W. Francis
Publication year - 2017
Publication title -
the brown university psychopharmacology update
Language(s) - English
Resource type - Journals
eISSN - 1556-7532
pISSN - 1068-5308
DOI - 10.1002/pu.30220
Subject(s) - paliperidone , medicine , paliperidone palmitate , bipolar disorder , antipsychotic , psychiatry , schizophrenia (object oriented programming) , psychotropic agent , pharmacology , cognition
Antiepileptic drugs are frequently used in the management of psychiatric conditions, particularly bipolar disorder. Since most psychotropic agents and antiepileptic drugs share the same metabolic pathways for elimination, there is a high likelihood of interactions between these two groups of drugs. Investigators recently examined the interaction potential between valproate and the atypical antipsychotic paliperidone in healthy volunteers and in patients with psychiatric disorders.