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Study shows lower antidepressant response in adults affected by childhood trauma
Publication year - 2016
Publication title -
the brown university psychopharmacology update
Language(s) - English
Resource type - Journals
eISSN - 1556-7532
pISSN - 1068-5308
DOI - 10.1002/pu.30167
Subject(s) - antidepressant , sertraline , depression (economics) , medicine , psychiatry , fluoxetine , clinical psychology , childhood abuse , poison control , injury prevention , anxiety , child abuse , emergency medicine , economics , macroeconomics , receptor , serotonin
A depression treatment study that found a high likelihood of early‐life stress in patients with depression has also found that abuse experienced at age 7 or younger predicted worse outcomes from antidepressant treatment in adulthood. The outcome findings, which were most robust for patients receiving sertraline, suggest that assessing for childhood trauma might serve as an important component of treatment for depression, the researchers stated. Study results were published online May 3 in Translational Psychiatry .