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Citicoline has early effect on cocaine use in bipolar disorder patients
Publication year - 2015
Publication title -
the brown university psychopharmacology update
Language(s) - English
Resource type - Journals
eISSN - 1556-7532
pISSN - 1068-5308
DOI - 10.1002/pu.30076
Subject(s) - citicoline , bipolar disorder , psychopharmacology , mania , psychiatry , cocaine use , psychology , medicine , placebo , clinical psychology , pharmacology , lithium (medication) , alternative medicine , pathology
The endogenous nucleotide citicoline was effective in reducing cocaine use in a group of outpatients with cocaine dependence and bipolar I disorder, but the effects of the treatment diminished somewhat over time, a new study has found. Citicoline did not result in significant differences from placebo in manic or depressive symptoms, the researchers found.