Premium
Meta‐analysis finds small benefit for quetiapine in schizophrenia
Publication year - 2015
Publication title -
the brown university psychopharmacology update
Language(s) - English
Resource type - Journals
eISSN - 1556-7532
pISSN - 1068-5308
DOI - 10.1002/pu.30069
Subject(s) - quetiapine , schizophrenia (object oriented programming) , meta analysis , sedation , adverse effect , medicine , antipsychotic , quetiapine fumarate , antipsychotic drug , psychiatry , psychology , atypical antipsychotic , anesthesia , pharmacology
A systematic review and meta‐analysis has concluded that the immediate‐release formulation of the antipsychotic quetiapine has a small beneficial effect on overall symptoms of schizophrenia. The review found no evidence of increased risk of serious adverse events but did indicate that the drug generates a moderate to large effect on weight gain and also leads to sedation in a significant number of cases.