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Study: Older users of antipsychotics have higher‐than‐expected death risk
Publication year - 2015
Publication title -
the brown university psychopharmacology update
Language(s) - English
Resource type - Journals
eISSN - 1556-7532
pISSN - 1068-5308
DOI - 10.1002/pu.30057
Subject(s) - quetiapine , medicine , antipsychotic , haloperidol , dementia , psychiatry , retrospective cohort study , risperidone , schizophrenia (object oriented programming) , typical antipsychotic , pediatrics , atypical antipsychotic , disease , dopamine
A retrospective study of elderly adults with dementia has found a higher mortality risk from use of antipsychotic medications than what had been reported in earlier research. Among the individual antipsychotics examined in the study, haloperidol conferred the greatest risk and quetiapine the lowest, while the risk associated with atypical antipsychotics as a group increased with dose. Results were published online March 18 in JAMA Psychiatry .