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Intranasal ketamine shows rapid effects in depression study
Publication year - 2015
Publication title -
the brown university psychopharmacology update
Language(s) - English
Resource type - Journals
eISSN - 1556-7532
pISSN - 1068-5308
DOI - 10.1002/pu.30029
Subject(s) - ketamine , nasal administration , medicine , crossover study , antidepressant , depression (economics) , anesthesia , treatment resistant depression , double blind , pharmacology , placebo , hippocampus , alternative medicine , pathology , economics , macroeconomics
A new randomized, double‐blind crossover study has found that a single 50‐mg dose of intranasal ketamine was associated with rapid antidepressant response in patients with treatment‐resistant depression, with a significant effect seen 40 minutes after administration.