Premium
Effect of the antiulcer polysaccharide fraction from Bupleurum falcatum L. on the healing of gastric ulcer induced by acetic acid in rats
Author(s) -
Matsumoto T.,
Sun X. B.,
Hanawa T.,
Kodaira H.,
Ishii K.,
Yamada H.
Publication year - 2002
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.986
Subject(s) - acetic acid , traditional medicine , polysaccharide , medicine , peptic ulcer , wound healing , pharmacognosy , pharmacology , chemistry , gastroenterology , biochemistry , biological activity , surgery , in vitro
An antiulcer polysaccharide fraction (BR‐2) from Bupleurum falcatum L. was examined for its effect on the healing of chronic ulcers induced by acetic acid in rats. When BR‐2 was administered orally to the rats, it was shown to be effective in the healing of acetic acid‐induced chronic ulcer. This result suggests that the use of herbal prescriptions containing B. falcatum L. may prove useful for the treatment of peptic ulcers. Copyright © 2002 John Wiley & Sons, Ltd.