Human platelet aggregation inhibitors from thyme ( Thymus vulgaris  L.) | Zendy

Okazaki Kenji | Zendy; Kawazoe Kazuyoshi | Zendy; Takaishi Yoshihisa | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Human platelet aggregation inhibitors from thyme ( Thymus vulgaris L.)

Author(s) -

Okazaki Kenji,

Kawazoe Kazuyoshi,

Takaishi Yoshihisa

Publication year - 2002

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.979

Subject(s) - thymus vulgaris , arachidonic acid , thymol , thrombin , chemistry , platelet aggregation , platelet , pharmacognosy , stereochemistry , biochemistry , biological activity , in vitro , enzyme , biology , chromatography , immunology , essential oil

Two antiaggregant compounds, thymol (compound 1) and 3,4,3′,4′‐tetrahydroxy‐5,5′‐diisopropyl‐2,2′‐dimethylbiphenyl (compound 2) were isolated from the leaves of thyme ( Thymus vulgaris L.). The structures were determined by 1 H‐, 13 C‐NMR and mass spectra (MS) studies. These compounds inhibited platelet aggregation induced by collagen, ADP, arachidonic acid (AA) and thrombin except that compound 2 did not inhibit platelet aggregation induced by thrombin. Copyright © 2002 John Wiley & Sons, Ltd.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research