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Effects of black radish root (Raphanus sativus L. var niger ) on the colon mucosa in rats fed a fat rich diet
Author(s) -
Sipos P,
Hagymási K,
Lugasi A,
Fehér E,
Blázovics A
Publication year - 2002
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.950
Subject(s) - raphanus , inflammation , antioxidant , biology , botany , biochemistry , immunology
The effect of black radish root ( Raphanus sativus L. var niger ) was studied on the structure and redox state of the colon mucosa in fat‐rich diet fed rats. The epithelial lining disrupted, the number of enterocytes and the goblet cells reduced and inflammatory cells were observed in rats fed with a fat‐rich diet. After treatment with granules from black radish root all of the histopathological changes and parameters of the redox state caused by the fat‐rich diet were improved. The structure of the epithelial cells was similar to the controls, the number of goblet cells increased and no inflammation was observed. Copyright © 2002 John Wiley & Sons, Ltd.