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Protection of DNA and microsomal membranes in vitro by Glycyrrhiza glabra L. against gamma irradiation
Author(s) -
Shetty T. K.,
Satav J. G.,
Nair C. K. K.
Publication year - 2002
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.927
Subject(s) - glycyrrhiza , lipid peroxidation , microsome , in vitro , dna , membrane , chemistry , biochemistry , dna damage , biology , microbiology and biotechnology , antioxidant , medicine , alternative medicine , pathology
The radioprotective effect of the root extract of Glycyrrhiza glabra L on lipid peroxidation in rat liver microsomes and plasmid pBR322 DNA was investigated. The extract was found to protect microsomal membranes, as evident from reduction in lipid peroxidation, and could also protect plasmid DNA from radiation‐induced strand breaks. Copyright © 2002 John Wiley & Sons, Ltd.