The presence of antiamoebic constituents in Psyllium husk | Zendy

Zaman Viqar | Zendy; Manzoor Syed Munazza | Zendy; Zaki Mehreen | Zendy; Aziz Nauman | Zendy; Gilani AnwarulHassan | Zendy

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The presence of antiamoebic constituents in Psyllium husk

Author(s) -

Zaman Viqar,

Manzoor Syed Munazza,

Zaki Mehreen,

Aziz Nauman,

Gilani AnwarulHassan

Publication year - 2002

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.886

Subject(s) - plantago ovata , psyllium , entamoeba histolytica , entamoeba , fraction (chemistry) , husk , petroleum ether , traditional medicine , pharmacognosy , plantaginaceae , chemistry , dysentery , plantago , food science , chromatography , biology , botany , microbiology and biotechnology , biological activity , biochemistry , medicine , in vitro , dietary fiber , extraction (chemistry)

The crude extract of psyllium husk (ispaghula) and its active constituent (petroleum fraction) caused varying degrees of growth inhibition in three different species of Entamoeba , i.e. Entamoeba histolytica, E. invadens and E. dispar . The inhibitory effect of the crude extract was in the dose range of 1–10 mg/mL, whereas a similar inhibitory effect was obtained with the petroleum fraction at a much lower dose (0.1–1.0 mg/mL), indicating that the active chemical(s) is/are concentrated in the petroleum fraction. These data support the traditional use of psyllium husk in amoebic dysentery. Copyright © 2002 John Wiley & Sons, Ltd.

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