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Analgesic and antiinflammatory properties of Sideritis lotsyi var. Mascaensis
Author(s) -
HernándezPérez Margarita,
Rabanal Gallego Rosa M.
Publication year - 2002
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.866
Subject(s) - analgesic , antimicrobial , traditional medicine , chloroform , chemistry , lamiaceae , carrageenan , ethanol , acetic acid , pharmacognosy , pharmacology , medicine , chromatography , biological activity , in vitro , biochemistry , organic chemistry
The antiinflammatory, analgesic and antimicrobial activities of crude ethanol extracts of Sideritis lotsyi var. mascaensis (Lamiaceae), and chloroform and aqueous fractions were evaluated in mice using paw and ear oedema induced by carrageenan and 12‐o‐tetradecanoyl‐phorbol‐acetate (TPA), respectively, as inflammation models, the writhing test induced by acetic acid for evaluating analgesic activity and the disk‐diffusion method for testing antimicrobial actions. The results obtained demonstrated significant topical antiinflammatory and analgesic activities for the ethanol extract and chloroform fraction, but no relevant antimicrobial activity against the microorganisms tested. Copyright © 2002 John Wiley & Sons, Ltd.