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Cytostatic activity of Achillea ageratum L.
Author(s) -
Gómez M. A.,
García M. D.,
Sáenz M. T.
Publication year - 2001
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.837
Subject(s) - chloroform , asteraceae , achillea , stigmasterol , traditional medicine , pharmacognosy , artemisia , in vitro , biology , botany , chemistry , biological activity , chromatography , medicine , biochemistry
The cytostatic activity of a chloroform extract and two isolated compounds from Achillea ageratum L. (Asteraceae) was determined in vitro against Hep‐2 and McCoy cells. The chloroform extract exhibited a high degree of growth inhibition compared with the values obtained with the 6‐mercaptopurine (positive control) against both cultures. Stigmasterol and β‐sitosterol, isolated from the chloroform extract, showed a high degree of growth inhibition. Copyright © 2001 John Wiley & Sons, Ltd.