Cytostatic activity of  Achillea ageratum  L. | Zendy

Gómez M. A. | Zendy; García M. D. | Zendy; Sáenz M. T. | Zendy

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Cytostatic activity of Achillea ageratum L.

Author(s) -

Gómez M. A.,

García M. D.,

Sáenz M. T.

Publication year - 2001

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.837

Subject(s) - chloroform , asteraceae , achillea , stigmasterol , traditional medicine , pharmacognosy , artemisia , in vitro , biology , botany , chemistry , biological activity , chromatography , medicine , biochemistry

The cytostatic activity of a chloroform extract and two isolated compounds from Achillea ageratum L. (Asteraceae) was determined in vitro against Hep‐2 and McCoy cells. The chloroform extract exhibited a high degree of growth inhibition compared with the values obtained with the 6‐mercaptopurine (positive control) against both cultures. Stigmasterol and β‐sitosterol, isolated from the chloroform extract, showed a high degree of growth inhibition. Copyright © 2001 John Wiley & Sons, Ltd.

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