Investigation of the larvicidal activity of  Pothomorphe peltata  and isolation of the active constituent | Zendy

Mongelli E. | Zendy; Coussio J. | Zendy; Ciccia G. | Zendy

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Investigation of the larvicidal activity of Pothomorphe peltata and isolation of the active constituent

Author(s) -

Mongelli E.,

Coussio J.,

Ciccia G.

Publication year - 2002

Publication title -

phytotherapy research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 129

eISSN - 1099-1573

pISSN - 0951-418X

DOI - 10.1002/ptr.753

Subject(s) - aedes aegypti , piperaceae , traditional medicine , biological activity , pharmacognosy , biology , larvicide , fractionation , larva , piper , botany , chemistry , chromatography , biochemistry , in vitro , medicine

The insecticidal activity of the leaves of Pothomorphe peltata (Piperaceae) was evaluated on Aedes aegypti larvae. The active methanol extract was subjected to a bioactivity‐directed fractionation, monitored by the larvicidal assay, and led to the isolation of a catechol derivative, 4‐nerolidylcatechol. This compound was quite potent against Aedes aegypti larvae (LC 50 = 9.1 µg/mL). Copyright © 2002 John Wiley & Sons, Ltd.

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