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Analgesic and antiinflammatory activities of vernonioside B2 from Vernonia condensata
Author(s) -
Valverde A. L.,
Cardoso G. L. C.,
Pereira N. A.,
Silva A. J. R.,
Kuster R. M.
Publication year - 2001
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.733
Subject(s) - analgesic , acetic acid , traditional medicine , herb , in vivo , pharmacognosy , medicine , pharmacology , chemistry , biological activity , medicinal herbs , in vitro , biochemistry , biology , microbiology and biotechnology
Vernonioside B2 isolated from the methanol extract of the Brazilian herb Vernonia condensata Baker was evaluated in vivo for analgesic and antiinflammatory activities. The compound reduced writhings (93.28%) and Evans blue dye diffusion (91.80%) induced by acetic acid (0.1 N) in a dose‐dependent manner. Copyright © 2001 John Wiley & Sons, Ltd.