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Promising traditional Indian medicinal plants for the management of novel Coronavirus disease: A systematic review
Author(s) -
Singh Rahul Soloman,
Singh Ashutosh,
Kaur Harpinder,
Batra Gitika,
Sarma Phulen,
Kaur Hardeep,
Bhattacharyya Anusuya,
Sharma Amit Raj,
Kumar Subodh,
Upadhyay Sujata,
Tiwari Vinod,
Avti Pramod,
Prakash Ajay,
Medhi Bikash
Publication year - 2021
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.7150
Subject(s) - traditional medicine , medicine , siddha , medicinal plants , withania somnifera , ocimum , zingiber officinale , tinospora cordifolia , asparagus racemosus , naturopathy , alternative medicine , pathology
Traditional Indian medical practices (Ayurveda, Siddha, Unani, and homeopathy) are a vast reservoir of knowledge about medicinal plants. The promising pharmacological properties of these plants have paved the way for developing therapy against novel Coronavirus (CoV) infection. The current review will summarize published works of literature on the effects of traditional Indian medicinal plants against acute respiratory infection (COVID‐19, SARS, Influenza, and Respiratory syncytial virus infection) and registered clinical trials of traditional Indian herbal medicines in COVID‐19. The current study aims to comprehensively evaluate the data of traditional Indian medicinal plants to warrant their use in COVID‐19 management. PubMed, Embase, and Cochrane databases were searched along with different clinical trial databases. A total of 22 relevant traditional Indian medicinal plants (35 relevant studies) were included in the current study having potential antiviral properties against virus‐induced respiratory illness along with promising immunomodulatory and thrombolytic properties. Further, 36 randomized and nonrandomized registered clinical trials were also included that were aimed at evaluating the efficacy of herbal plants or their formulations in COVID‐19 management. The antiviral, immunomodulatory, and thrombolytic activities of the traditional Indian medicinal plants laid down a strong rationale for their use in developing therapies against SARS‐CoV‐2 infection. The study identified some important potential traditional Indian medicinal herbs such as Ocimum tenuiflorum , Tinospora cordifolia , Achyranthes bidentata , Cinnamomum cassia , Cydonia oblonga , Embelin ribes , Justicia adhatoda , Momordica charantia , Withania somnifera , Zingiber officinale , Camphor, and Kabusura kudineer, which could be used in therapeutic strategies against SARS‐CoV‐2 infection.