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Curcumin nanoformulations for antimicrobial and wound healing purposes
Author(s) -
Salehi Bahare,
Rodrigues Célia F.,
Peron Gregorio,
Dall'Acqua Stefano,
SharifiRad Javad,
Azmi Lubna,
Shukla Ila,
Singh Baghel Uttam,
Prakash Mishra Abhay,
Elissawy Ahmed M.,
Singab Abdel Nasser,
Pezzani Raffaele,
Redaelli Marco,
Patra Jayanta Kumar,
Kulandaisamy Venil Chidambaram,
Das Gitishree,
Singh Deeksha,
Kriplani Priyanka,
Venditti Alessandro,
Fokou Patrick Valere Tsouh,
Iriti Marcello,
Amarowicz Ryszard,
Martorell Miquel,
CruzMartins Natália
Publication year - 2021
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.6976
Subject(s) - curcumin , antimicrobial , curcuma , wound healing , bioavailability , medicine , pharmacology , traditional medicine , microbiology and biotechnology , biology , surgery
The development and spread of resistance to antimicrobial drugs is hampering the management of microbial infectious and wound healing processes. Curcumin is the most active and effective constituent of Curcuma longa L., also known as turmeric, and has a very long and strong history of medicinal value for human health and skincare. Curcumin has been proposed as strong antimicrobial potentialities and many attempts have been made to determine its ability to conjointly control bacterial growth and promote wound healing. However, low aqueous solubility, poor tissue absorption and short plasma half‐life due its rapid metabolism needs to be solved for made curcumin formulations as suitable treatment for wound healing. New curcumin nanoformulations have been designed to solve the low bioavailability problem of curcumin. Thus, in the present review, the therapeutic applications of curcumin nanoformulations for antimicrobial and wound healing purposes is described.