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Antiinflammatory and antioxidant property of saponins of tea [ Camellia sinensis (L) O. Kuntze] root extract
Author(s) -
Sur P.,
Chaudhuri T.,
Vedasiromoni J. R.,
Gomes A.,
Ganguly D. K.
Publication year - 2001
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.696
Subject(s) - camellia sinensis , antioxidant , xanthine oxidase , traditional medicine , chemistry , saponin , carrageenan , pharmacognosy , theaceae , in vitro , biological activity , biochemistry , botany , biology , enzyme , medicine , alternative medicine , pathology
Two groups of saponins, TS‐1 and TS‐2, isolated from tea root extract (TRE) were tested for antiinflammatory and in vitro antioxidant activity. Both TS‐1 and TS‐2 inhibited carrageenan‐induced paw oedema in rats. The antioxidant activity of these compounds was evaluated using the xanthine–xanthine oxidase system. The study indicated that the previously observed antitumour activity of TRE might be mediated through scavenging of free radicals by saponins and their antiinflammatory activity. Copyright © 2001 John Wiley & Sons, Ltd.