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A pharmacology‐based comprehensive review on medicinal plants and phytoactive constituents possibly effective in the management of COVID ‐19
Author(s) -
Jalali Atefeh,
Dabaghian Farid,
Akbrialiabad Hossein,
Foroughinia Farzaneh,
Zarshenas Mohammad M.
Publication year - 2021
Publication title -
phytotherapy research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 129
eISSN - 1099-1573
pISSN - 0951-418X
DOI - 10.1002/ptr.6936
Subject(s) - traditional medicine , medicinal plants , medicine , ginseng , andrographis paniculata , pharmacology , alternative medicine , pathology
Arisen in China, COVID‐19 (SARS‐CoV‐II) is a novel coronavirus that has been expanding fast worldwide. Till now, no definite remedial drug or vaccine has been identified for COVID‐19 treatment. Still, for a majority of infected patients, supportive therapy is the cornerstone of the management plan. To the importance of managing the COVID‐19 pandemic, this article proposed to collecting capable medicinal plants and bioactive components in both treat and supportive therapy of this novel viral infection. Clinical points in the pathogenesis, symptoms, and complications of COVID‐19 were considered. The effective plants and bioactives that may play a role in supportive therapy/management of COVID‐19 were searched, collected through the “Scopus” database and listed in three sections. Numerous medicinal plants such as Citrus Spp., Camellia sinensis , and Glycyrrhiza glabra can interference with COVID‐19 pathogenesis via inhibition of virus replication and entry to its host cells. Also, some anti‐inflammatory herbal medicine such as Andrographis paniculata , Citrus spp., and Cuminum cyminum can relieve fever and cough in COVID‐19 patients. Medicinal plants such as G. glabra , Thymus vulgaris , Allium sativum , Althea officinalis , and Panax ginseng may modulate the immune system and possess prevention and supportive therapy. However, more clinical data are required to confirm these hypotheses.